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Xeomin vs. Botox: Which Neuromodulator is Right for You?

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Xeomin and Botox are both neuromodulators, meaning they work by temporarily relaxing the muscles in the face to reduce the appearance of fine lines and wrinkles. They share the same efficacy, and typically last around four months.  

Botox is the original neuromodulator and has been used for cosmetic purposes for over 20 years. Botox is made of botulinum toxin type A, plus a complex mixture of carrier proteins. 

Xeomin is a purified form of botulinum toxin type A, the same active ingredient in Botox. This may make Xeomin a better option for people who are sensitive to additives or who have a history of allergic reactions to Botox. Additionally, Xeomin’s lack of carrier proteins ensures clients will not build resistance to the neuromodulator, a common problem with Botox.  

Origins of Botox:  Botox was first developed in the 1970s to treat strabismus (crossed eyes) and blepharospasm (uncontrollable blinking). It was approved by the FDA for cosmetic use in 2002. 

Origins of Xeomin: Xeomin was first developed in Germany in the early 2000s and was approved by the FDA in 2011. It is now available in over 30 countries worldwide. 

Both Xeomin and Botox can be used to treat a variety of cosmetic concerns, including:  

-Frown lines 

-Forehead wrinkles 

-Crow's feet 

-Gummy smile 

-Jawline slimming 

-Lip lines 

-Neck lines 

Choosing Between Xeomin and Botox: The best way to decide which neuromodulator is right for you is to talk to your doctor. They can assess your individual needs and goals and recommend the best treatment for you 

Xeomin V.S. Botox:


Active ingredient: Botulinum toxin type A 

Onset of action: 3-7 days 

Additives: None 

Results last: Around 4 months 


Active ingredient: Botulinum toxin type A 

Onset of action: 4-7 days

Additives: Complex mixture of proteins 

Results last: Around 4 months 

Additives: Botox contains added complex proteins, If you are concerned about additives, Xeomin may be a better option for you. Some consider it the more natural, or “naked’ alternative to Botox.  

Previous experience: If you have not had success with Botox in the past, Xeomin may be a better option for you.  

Efficacy: Xeomin is just as effective as Botox at reducing wrinkles and fine lines. They both typically last around 4 months. Sometimes Xeomin results show slightly faster than Botox due to the lack of complex proteins present in the neuromodulator.  

* All information subject to change. Images may contain models. Individual results are not guaranteed and may vary.